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Traumatic rhabdomyolysis

MedGen UID:
592957
•Concept ID:
C0410257
•
Disease or Syndrome
Synonym: Muscle crush syndrome
SNOMED CT: Traumatic rhabdomyolysis (240125008); Muscle crush syndrome (240125008)

Professional guidelines

PubMed

Non-traumatic rhabdomyolysis: Background, laboratory features, and acute clinical management.
Cervellin G, Comelli I, Benatti M, Sanchis-Gomar F, Bassi A, Lippi G
Clin Biochem 2017 Aug;50(12):656-662. Epub 2017 Feb 21 doi: 10.1016/j.clinbiochem.2017.02.016. PMID: 28235546
Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited.
Nielsen JS, Sally M, Mullins RJ, Slater M, Groat T, Gao X, de la Cruz JS, Ellis MK, Schreiber M, Malinoski DJ
Am J Surg 2017 Jan;213(1):73-79. Epub 2016 Jun 14 doi: 10.1016/j.amjsurg.2016.03.017. PMID: 27381816
Pre-hospital treatment of traumatic rhabdomyolysis.
Desjardins M, Strange B
Emerg Nurse 2013 Dec;21(8):28-33. doi: 10.7748/en2013.12.21.8.28.e1221. PMID: 24313421

Recent clinical studies

Etiology

Traumatic rhabdomyolysis: rare but morbid, potentially lethal, and inconsistently monitored.
Giles T, King K, Meakes S, Weaver N, Balogh ZJ
Eur J Trauma Emerg Surg 2024 Jun;50(3):1063-1071. Epub 2024 Mar 27 doi: 10.1007/s00068-023-02420-8. PMID: 38536468Free PMC Article
CRUSH SYNDROME IN EARTHQUAKES - STAY AND PLAY OR LOAD AND GO?
Nola IA, Dvorski M, Žižak M, Kuliš T
Acta Clin Croat 2023 Jul;62(Suppl2):158-165. doi: 10.20471/acc.2023.62.s2.24. PMID: 38966034Free PMC Article
Drugs and Rhabdomyolysis: From Liver to Kidney.
Barbano B, Sardo L, Gasperini ML, Gigante A, Liberatori M, Di Lazzaro GG, Di Mario F, Dorelli B, Amoroso A, Cianci R
Curr Vasc Pharmacol 2015;13(6):725-37. doi: 10.2174/1570161113666150130151839. PMID: 25633322
Non-traumatic rhabdomyolysis and diabetes.
Sani MA, Campana-Salort E, Begu-LeCorroller A, Baccou M, Valéro R, Vialettes B
Diabetes Metab 2011 Jun;37(3):262-4. Epub 2011 May 7 doi: 10.1016/j.diabet.2011.03.003. PMID: 21550832
Hypokalaemic rhabdomyolysis.
Kishore B, Thurlow V, Kessel B
Ann Clin Biochem 2007 May;44(Pt 3):308-11. doi: 10.1258/000456307780480882. PMID: 17456302

Diagnosis

Traumatic Rhabdomyolysis: Crush Syndrome, Compartment Syndrome, and the 'Found Down' Patient.
Fernandez JJ, Smith SR
J Am Acad Orthop Surg 2024 Feb 15;32(4):e166-e174. Epub 2023 Dec 13 doi: 10.5435/JAAOS-D-23-00734. PMID: 38109720
Destructive disasters, trauma, crush syndrome, and beyond.
Sever MS, Katı YA, Özkaya U
Acta Orthop Traumatol Turc 2023 Nov;57(6):305-314. doi: 10.5152/j.aott.2023.23147. PMID: 38454211Free PMC Article
Non-traumatic rhabdomyolysis: Background, laboratory features, and acute clinical management.
Cervellin G, Comelli I, Benatti M, Sanchis-Gomar F, Bassi A, Lippi G
Clin Biochem 2017 Aug;50(12):656-662. Epub 2017 Feb 21 doi: 10.1016/j.clinbiochem.2017.02.016. PMID: 28235546
Non-traumatic rhabdomyolysis and diabetes.
Sani MA, Campana-Salort E, Begu-LeCorroller A, Baccou M, Valéro R, Vialettes B
Diabetes Metab 2011 Jun;37(3):262-4. Epub 2011 May 7 doi: 10.1016/j.diabet.2011.03.003. PMID: 21550832
Crush injury and rhabdomyolysis.
Malinoski DJ, Slater MS, Mullins RJ
Crit Care Clin 2004 Jan;20(1):171-92. doi: 10.1016/s0749-0704(03)00091-5. PMID: 14979336

Therapy

Traumatic Rhabdomyolysis: Crush Syndrome, Compartment Syndrome, and the 'Found Down' Patient.
Fernandez JJ, Smith SR
J Am Acad Orthop Surg 2024 Feb 15;32(4):e166-e174. Epub 2023 Dec 13 doi: 10.5435/JAAOS-D-23-00734. PMID: 38109720
Non-traumatic rhabdomyolysis: Background, laboratory features, and acute clinical management.
Cervellin G, Comelli I, Benatti M, Sanchis-Gomar F, Bassi A, Lippi G
Clin Biochem 2017 Aug;50(12):656-662. Epub 2017 Feb 21 doi: 10.1016/j.clinbiochem.2017.02.016. PMID: 28235546
Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited.
Nielsen JS, Sally M, Mullins RJ, Slater M, Groat T, Gao X, de la Cruz JS, Ellis MK, Schreiber M, Malinoski DJ
Am J Surg 2017 Jan;213(1):73-79. Epub 2016 Jun 14 doi: 10.1016/j.amjsurg.2016.03.017. PMID: 27381816
Non-traumatic rhabdomyolysis and diabetes.
Sani MA, Campana-Salort E, Begu-LeCorroller A, Baccou M, Valéro R, Vialettes B
Diabetes Metab 2011 Jun;37(3):262-4. Epub 2011 May 7 doi: 10.1016/j.diabet.2011.03.003. PMID: 21550832
Hypokalaemic rhabdomyolysis.
Kishore B, Thurlow V, Kessel B
Ann Clin Biochem 2007 May;44(Pt 3):308-11. doi: 10.1258/000456307780480882. PMID: 17456302

Prognosis

Destructive disasters, trauma, crush syndrome, and beyond.
Sever MS, Katı YA, Özkaya U
Acta Orthop Traumatol Turc 2023 Nov;57(6):305-314. doi: 10.5152/j.aott.2023.23147. PMID: 38454211Free PMC Article
Factors predicting kidney replacement therapy in pediatric earthquake victims with crush syndrome in the first week following rescue.
Atmis B, Bayazit AK, Cagli Piskin C, Saribas E, Piskin FC, Bilen S, Ozgur Horoz O, Ekinci F, Turker I, Telefon HA, Unal I, Yilmaz HL, Narli N, Yildizdas D
Eur J Pediatr 2023 Dec;182(12):5591-5598. Epub 2023 Oct 7 doi: 10.1007/s00431-023-05250-3. PMID: 37804325
Management of Severe Crush Injuries in Austere Environments: A Special Operations Perspective.
Anderson JL, Cole M, Pannell D
J Spec Oper Med 2022 May 31;22(2):43-47. doi: 10.55460/2Y7A-IGK7. PMID: 35639893
Non-traumatic rhabdomyolysis: Background, laboratory features, and acute clinical management.
Cervellin G, Comelli I, Benatti M, Sanchis-Gomar F, Bassi A, Lippi G
Clin Biochem 2017 Aug;50(12):656-662. Epub 2017 Feb 21 doi: 10.1016/j.clinbiochem.2017.02.016. PMID: 28235546
Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited.
Nielsen JS, Sally M, Mullins RJ, Slater M, Groat T, Gao X, de la Cruz JS, Ellis MK, Schreiber M, Malinoski DJ
Am J Surg 2017 Jan;213(1):73-79. Epub 2016 Jun 14 doi: 10.1016/j.amjsurg.2016.03.017. PMID: 27381816

Clinical prediction guides

Factors predicting kidney replacement therapy in pediatric earthquake victims with crush syndrome in the first week following rescue.
Atmis B, Bayazit AK, Cagli Piskin C, Saribas E, Piskin FC, Bilen S, Ozgur Horoz O, Ekinci F, Turker I, Telefon HA, Unal I, Yilmaz HL, Narli N, Yildizdas D
Eur J Pediatr 2023 Dec;182(12):5591-5598. Epub 2023 Oct 7 doi: 10.1007/s00431-023-05250-3. PMID: 37804325
Study of the Relationship Between Liver Function Markers and Traumatic Rhabdomyolysis: A Retrospective Study of Hemorrhagic Patients Admitted to Intensive Care Unit in a Level I Trauma Center.
Martinez T, Liaud-Laval G, Laitselart P, Pissot M, Chrisment A, Ponsin P, Duranteau O, De Rudnicki S, Boutonnet M, Libert N
Anesth Analg 2023 May 1;136(5):842-851. Epub 2023 Apr 14 doi: 10.1213/ANE.0000000000006406. PMID: 37058720
Management of Severe Crush Injuries in Austere Environments: A Special Operations Perspective.
Anderson JL, Cole M, Pannell D
J Spec Oper Med 2022 May 31;22(2):43-47. doi: 10.55460/2Y7A-IGK7. PMID: 35639893
Psychosis-Induced Exertional Rhabdomyolysis without Acute Kidney Injury or Myoglobinuria.
Butkus JM, Kramer M, Chan V, Kim E
Am J Case Rep 2022 Jan 3;23:e934943. doi: 10.12659/AJCR.934943. PMID: 34975144Free PMC Article
Bicarbonate and mannitol treatment for traumatic rhabdomyolysis revisited.
Nielsen JS, Sally M, Mullins RJ, Slater M, Groat T, Gao X, de la Cruz JS, Ellis MK, Schreiber M, Malinoski DJ
Am J Surg 2017 Jan;213(1):73-79. Epub 2016 Jun 14 doi: 10.1016/j.amjsurg.2016.03.017. PMID: 27381816

Recent systematic reviews

Uric acid in predicting the traumatic rhabdomyolysis induced acute kidney injury; a systematic review and meta-analysis.
Safari S, Ghasemi M, Yousefifard M, Ghasemi A, Najafi I
BMC Nephrol 2024 Mar 5;25(1):82. doi: 10.1186/s12882-024-03509-x. PMID: 38443920Free PMC Article

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